Trial of Anifrolumab in Active Systemic Lupus Erythematosus

N Engl J Med 2020:211–20

Morand et al demonstrate a greater BICLA response at Week 52 for patients treated with anifrolumab versus those treated with placebo.

Significant benefits of anifrolumab versus placebo were also seen in glucocorticoid dose and severity of skin disease. A greater frequency of HZ was seen in patients treated with anifrolumab versus placebo.


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