Long-term Outcome Of A Randomised Controlled Trial Comparing Tacrolimus With Mycophenolate Mofetil As Induction Therapy For Active Lupus Nephritis
Ann Rheum Dis 2020;79:1070–6
Tacrolimus is non inferior to MMF as an induction therapy for LN.
This study by Mok et al. looks at ten-year data from a large cohort of patients with LN treated with either tacrolimus or MMF and shows no significant differences between the two treatments in terms of renal flares or renal function decline. Therefore, tacrolimus may be considered as an alternative to MMF as an induction therapy for LN. |