Mycophenolate Versus Azathioprine As Maintenance Therapy for Lupus Nephritis
N Engl J Med. 2011;365(20):1886–95
MMF was superior to AZA in maintaining a renal response and preventing relapse in patients with LN who had a response to induction therapy.
In the results of this 36-month, randomised, double-blind, Phase 3 study, Dooley et al demonstrate an improvement in times to treatment failure, rescue therapy and renal flare, as well as a lower rate of treatment failure in the MMF group versus the AZA group.
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