Effect and safety profile of belimumab and tacrolimus combination therapy in thirty‑three patients with systemic lupus erythematosus

Clin Rheumatol. 2022. Epub ahead of print doi: 10.1007/s10067-022-06325-6

Although combined belimumab and mycophenolate mofetil treatment has been proven to be effective in patients with SLE, to date, the safety and effectiveness of belimumab-calcineurin inhibitor combination therapy has not been addressed. As such, Nakai, et al. retrospectively analysed data from 33 patients in a tertiary teaching hospital, to establish the safety/efficacy profile of belimumab-tacrolimus combination therapy in patients with SLE.


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