Evaluation of the LFA-REAL Clinician-reported Outcome (ClinRO) and Patient-reported Outcome (PRO): Prespecified Analysis of the Phase III Ustekinumab Trial in Patients with SLE
Lupus Sci Med. 2023 doi:10.1136/lupus-2022-000875
The Lupus Foundation of America Rapid Evaluation of Activity in Lupus (LFA-REAL) clinician-reported outcome (ClinRO) and patient-reported outcome (PRO) systems show potential as a flexible resource in the evaluation of lupus disease activity and a simple, user-friendly outcome measure for SLE studies.
With the heterogeneity and variability of SLE clinical pattern and disease course making it challenging to accurately measure disease activity, there is need for a system that can capture a more complete disease activity, in practice and clinical research. To help address this, Askanase, et al. evaluated the LFA-REAL system, comparing its outcomes with other SLE disease activity measure.