Does Remission in Systemic Lupus Erythematosus According to the 2021 DORIS Definition Match the Treating Rheumatologist’s Judgment?

Rheumatology (Oxford) 2023;63(1):72–8 doi: 10.1093/rheumatology/kead159

Assessment on agreement between the 2021 DORIS and physician-judged lupus activity finds the 2021 DORIS remission to be an achievable target in clinical practice, with substantial agreement between the DORIS definition and physician-judged remission.

Various definitions of remission in SLE have been proposed, most recently, the 2021 Definition of Remission In SLE (DORIS). But, whether the criteria for DORIS are concordant with treating physicians’ judgment on whether their patient is in remission in real-life clinical practice, has yet to be established. To help address this, González, et al. evaluated the rate of 2021 DORIS remission in a large multicentre cohort of SLE patients in a clinical setting and its agreement with the clinical status of remission as judged by treating physicians.