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October 2024

ANA-associated arthritis: clinical and biomarker characterization of a population for basket trials

Rheumatol 2024 2024;00:1–11 DOI 10.1093/rheumatology/keae269

Arnold et al. assessed musculoskeletal (MSK) inflammation in ANA-associated rheumatic diseases (RMDs) and redefined ANA-associated arthritis into two distinct multi-disease clusters based on disease activity, which may support a more targeted approach to treatment. The authors confirmed that MSK inflammation is a key feature across diagnoses and responded similarly to treatments.

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