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Published 2023 ▼
Date of upload Date of publication Published 2025 Published 2024 (Checked) Published 2023 Published 2022 Published 2021

Find coverage of the latest original articles on Lupus, focusing on those with data on therapeutic interventions and those that have clinical impact.

Literature Highlights

Literature review thumbnail: Literature Highlights - March 2025
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Literature Highlights - March 2025

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Keywords:

B-cell, BAFF, IL-6, biomarker, SLE, biologics, belimumab, mucocutaneous, disease activity, Anifrolumab, LLDAS, DORIS, Remission, LTE
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Showing 2 results for “baricitinib” published 2023.

March 2023
Publication thumbnail: Baricitinib for Systemic Lupus Erythematosus:  a Double-blind, Randomised, Placebo-controlled,  Phase 3 trial (SLE-BRAVE-II) View Slides

Baricitinib for Systemic Lupus Erythematosus: a Double-blind, Randomised, Placebo-controlled, Phase 3 trial (SLE-BRAVE-II)

Petri M
,
Bruce IN
,
Dörner T
,
Tanaka Y
,
Morand EF
,
Kalunian KC
,
Cardiel MH
,
Silk ME
,
Dickson CL
,
Meszaros G
,
Zhang L
,
Jia B
,
Zhao Y
,
McVeigh CJ
,
Mosca M

Lancet. 2023 doi: 10.1016/S0140-6736(22)02546-6

Negative results of SLE-BRAVE-II trial show that evidence for the efficacy of baricitinib in SLE is inconclusive.

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Keywords:

  • Baricitinib,
  • SLE-BRAVE-II,
  • systemic lupus erythematosus,
  • SLE,
  • Phase 3
Download Slides Access via PubMed
Publication thumbnail: Baricitinib for Systemic Lupus Erythematosus:  a Double-blind, Randomised, Placebo-controlled,  Phase 3 Trial (SLE-BRAVE-I) View Slides

Baricitinib for Systemic Lupus Erythematosus: a Double-blind, Randomised, Placebo-controlled, Phase 3 Trial (SLE-BRAVE-I)

Morand EF
,
Vital EM
,
Petri M
,
van Vollenhoven R
,
Wallace DJ
,
Mosca M
,
Furie RA
,
Silk ME
,
Dickson CL
,
Meszaros G
,
Jia B
,
Crowe B
,
de la Torre I
,
Dörner T.

Lancet. 2023 doi: 10.1016/S0140-6736(22)02607-1

Primary endpoint in SLE-BRAVE-I study was met for the 4 mg baricitinib group, however, key secondary endpoints were not.

more…

Keywords:

  • Baricitinib,
  • SLE-BRAVE-I,
  • systemic lupus erythematosus,
  • SLE,
  • Phase 3
Download Slides Access via PubMed
 
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