Front Immunol. 2023 14:1200732 DOI: 10.3389/fimmu.2023.1200732
Using data from a longitudinal cohort of SLE patients of Chinese origin, the authors identified risk factors for LN and developed a prediction model, RIFLE-LN, which demonstrated good performance in a testing cohort of 270 patients.
This study aimed to develop and validate a risk stratification strategy to predict LN risk among Chinese SLE patients. RIFLE-LN addresses unmet needs of personalised risk assessment and monitoring for LN in SLE, although further independent validation is warranted.