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April 2024

Smith-specific regulatory T cells halt the progression of lupus nephritis

Nat Commun. 2024 Feb 6;15(1):899 DOI: 10.1038/s41467-024-45056-x

Compared with polyclonal mock-transduced regulatory T cells (Tregs), Smith(Sm)-Tregs potently suppress Sm-specific pro-inflammatory responses in vitro and suppress disease progression in a humanised mouse model of lupus nephritis.

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