November 2021
October 2021

Two-Year, Randomised, Controlled Trial of Belimumab in Lupus Nephritis

N Engl J Med. 2020;383(12):1117–28.

LN occurs in 25–60% of patients with SLE. However, patients with LN are often excluded from clinical trials of SLE therapies.

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Baricitinib for Lupus Erythematosus: A Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial

Lancet 2018;392:222–31

This international Phase 2 study aimed to assess the efficacy and safety of baricitinib, an oral JAK-1 and -2 inhibitor, in patients with SLE who were not adequately controlled despite standard background therapy.

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